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Publicações e Prêmios

Publicações e Prêmios

Lista de publicações:


 Santana, I. M.; Jardim, I. C. S. F.; Breitkreitz, M. C. Sequential DoE approach for the multiproduct analysis of cholesterol-lowering drugs by ultra-high performance supercritical fluid chromatography. Aceito para publicação no Journal of Separation Science, 2020.

 Ribeiro, L. N. M.; da Silva, G. H. R; Couto, V. M.; de Castro, S. R.; Breitkreitz, M. C.; Martinez, C. S.; Igartúa, D.; Prieto M. J.; de Paula, E. Functional hybrid nanoemulsions for sumatriptan intranasal delivery. Aceito para publicação no Frontiers in Chemistry, section Medicinal and Pharmaceutical Chemistry, 2020.

 Guedes, L.; Santana, C.; Rutledge, D. N.; Pinto, L.; Jardim, I. C. S. F.; Melo, L. V.; Beppu, M.; Breitkreitz, M. C. Quantification of palm oil biactive compounds by ultra-high-performance supercritical fluid chromatography and chemometrics. Aceito para publicação no Canadian Journal of Chemical Engineering, 2020. 

 Mitsutake, H.; Neves, M. G.; Rutledge, D. N.; Poppi, R. J.; Breitkreitz, M. C. Extraction of information about structrural changes in a semisolid pharmaceutical formulation from near-infrared and Raman images by multivariate curve resolution-alternating least squares and ComDim. Aceito para publicação no Journal of Chemometrics, 2020. 

 Pinto, L.; Jardim, I. C. S. F.; Rutledge, D. N.; Breitkreitz, M. C. Multiblock modelling on the study of the kinetic degradation of rosuvastatin calcium in the presence of retention time shifts and rank deficiency. Analytica Chimica Acta, v. 1133, p. 77-87, 2020.

 Santana, F. B.; Souza, A. M.; Almeida, M. R.; Breitkreitz, M. C.; Filgueiras, P. R.; Sena, M. M.; Poppi, R. J. Experimento didático de quimiometria para classificação de óleos vegetais comestíveis por espectroscopia no infravermelho médio combinado com análise discriminante por mínimos quadrados parciais: Um tutorial, Parte V. Química Nova, v. 43, p. 371-381, 2020. 

 Ribeiro, L. N. M.; Franz-Montan, M.; Alcântara, A. C. S.; Breitkreitz, M. C.; Castro, S. R.; Guilherme, V. A.; Muniz, B. V.; Rodrigues da Silva, G. H.; de Paula, E. Hybrid nanofilms as topical anesthetics for pain-free procedures in dentistry. Scientific Reports, v. 10, p. 1-11, 2020. 

 Guilherme, V. A.; Ribeiro, L. N. M.; Alcântara, A. C. S; Castro, S. R.; da Silva, G. H.R.; da Silva, C. G.; Breitkreitz, M. C.; Clemente-Napimoga, J.; Macedo, C. G.; Abdalla, H. B.; Bonfante, R.; Cereda, C.M. S.; de Paula, E. Improved efficacy of naproxenloaded NLC for temporomandibular joint administration, Scientific Reports, v. 9, p. 1-11, 2019.

 Mitsutake, H.; Poppi, R.J.; Breitkreitz, M. C. Raman Imaging Spectroscopy: History, Fundamentals and Current Scenario of the Technique, v. 30, p. 2243-2258, 2019.

 Kitagaki, B.; T., Pinto, M.R.; Queiroz, A.; Breitkreitz M.C.; Rossi F.; Nagao, R. Multivariate Statistical Analysis of Chemical and Electrochemical Oscillators for an Accurate Frequency Selection. Physical Chemistry Chemical Physics (PCCP),v.  21, p. 16383–16860, 2019.

 Ferreira, J. A.; Santos, J. M.; Breitkreitz, M. C.; Ferreira, J. M. S.; Lins, P. M. P.; Farias, S. C.; de Morais, D. R.; Eberlin, M. N.; Bottoli, C. B. G. Characterization of the lipid profile from coconut (Cocos nucifera L.) oil of different varieties by electrospray ionization mass spectrometry associated with principal component analysis and independent component analysis. Food Research International, v. 123, p. 189–197, 2019.

 Mitsutake, H.; Ribeiro L.N.M.; da Silva, G. H. R.; Castro, S. R.; de Paula E.; Poppi, R J.; Breitkreitz, M.C. Evaluation of miscibility and polymorphism of synthetic and natural lipids for nanostructured lipid carrier (NLC) formulations by Raman mapping and multivariate curve resolution (MCR). European Journal of Pharmaceutical Sciences, v. 135, p. 51–59, 2019.

 Pinto, L.; Stecchi, F.; Breitkreitz, M.C.  A simplified and versatile multivariate calibration procedure for multiproduct quantification of pharmaceutical drugs in the presence of interferences using first order data and chemometrics. Microchemical Journal, v. 146, p. 202-209, 2019.

 Albano, J.M.R; Ribeiro; L.N.M.; Couto, V.M.; Barbosa, M.M.; da Silva, G.H.R; Breitkreitz, M.C.; de Paula, E.; Pickholtz, M. Rational design of polymer-lipid nanoparticles for docetaxel delivery. Colloids and surfaces B-Biointerfaces, v.175, p. 56-64, 2019.

 Mitsutake, H.; Castro, S. R.; de Paula, E.; Poppi, R.J.; Rutledge, D.N.;  Breitkreitz, M.C.  Comparison of different chemometric methods to extract chemical and physical information from Raman images of homogeneous and heterogeneous semi-solid pharmaceutical formulations. International Journal of Pharmaceutics, v. 552, p. 119-129, 2018.

 Galaverna, R.; Breitkreitz; M.C.; Pastre; J. C. Conversion of D-Fructose to 5-(Hydroxymethyl)furfural: Evaluating Batch and Continuous Flow Conditions by Design of Experiments and In-line FTIR Monitoring. ACS Sustainable Chemistry & amp; Engineering, v. 6, p. 4220-4230, 2018.

 De Lima, K.P.; Jardim, I.C.S.F.;  Breitkreitz; M.C. Study of the chromatographic parameters of ultra high performance supercritical fluid chromatography and method development using a design of experiments approach for the quantification of pesticides in lettuce. Journal of Separation Science, v. 16, p. 1-7, 2018.

 Rezende, C.A.; Atta, B.W.; Breitkreitz, M.C.; Simister, R.; Gomez, L.D.; Mcqueen-Mason, S. J. Optimization of biomass pretreatments using fractional factorial experimental design. Biotechnology for Biofuels, v. 11, p. 206-220, 2018.

 Ribeiro, L.N.M.; Franz-Montan, M.; Breitkreitz, M. C.; Silva, G.H.R.; Castro, S. R.; Guilherme, V. A.; Araujo, D.; de Paula, Eneida. Nanohybrid hydrogels designed for transbuccal anesthesia. International Journal of Nanomedicine, v. Volume 13, p. 6453-6463, 2018.

 Santos, J.M.; Pudenzi, M.A.; Wisniewski Jr, A.; Breitkreitz, M.C.; Eberlin, M. Optimization of Atmospheric Pressure Photoionization for the Crude Oil Analysis Using Ultra-High Resolution Mass Spectrometry. Journal of the Brazilian Chemical Society, v. 30, p. 819-829, 2018.

 da Silva, G. H. R.; Moraes, L.N.M.; Guilherme; V.; Castro, S.R.; Breitkreitz, M.C.; de Paula, E. Bupivacaine (S75:R25) loaded in Nanostructured lipid carriers: factorial design, HPLC quantification method and physicochemical stability study. Current Drug Delivery, v. 15, p. 388-396, 2018.

 Konatu, F.R.B.; Breitkreitz, M.C.; Jardim. I.C.S.F. Revisiting quick, easy, cheap, effective, rugged, and safe parameters for sample preparation in pesticide residue analysis of lettuce by liquid chromatography-tandem mass spectrometry. Journal of Chromatography (Print), v. 1482, p. 11-22, 2017.

 Carmo, T.R.; Breitkreitz, M.C.; Felisberti, M.I. Telechelic Poly(bisphenol Acarbonate) Synthesis by Glycolysis: A Response Surface Methodology Approach. Industrial & Engineering Chemistry Research, v. 56, p. 3983-3992, 2017.

 Ribeiro, L.N.M.; Breitkreitz, M.C.; Guilherme, V.A; da Silva, G.H.R.; Couto, V.M.; Castro, S.R.; de Paula, B.O.; Machado, D.; de Paula, E. Natural lipids-based NLC containing lidocaine: from pre-formulation to in vivo studies. European Journal of Pharmaceutical Sciences, v. 106, p. 102-112, 2017.

 da Silva, G.H.R.; Ribeiro, L.N.M.; Mitsutake, H.; Guilherme, V.A; Castro, S.R.; Poppi, R.J.; Breitkreitz, M.C; de Paula, E. Optimised NLC: a nanotechnological approach to improve the anaesthetic effect of bupivacaine. International Journal of Pharmaceutics , v. 529, p. 253-263, 2017.

 de Souza Guedes, L.; Jardim, I.C.S.F; de Melo, L.V.; Beppu, M.; Breitkreitz, M.C.; Santana, C.C. Study of the effect of the operating parameters on the separation of bioactive compounds of palm oil by ultra-high performance supercritical fluid chromatography using a design of experiments approach. Canadian Journal of Chemical Engineering, v. 9999, p. 1-9, 2017.

 Alexandrino, G. L.; Breitkreitz, M.C.; Poppi, R.J. Classical least squares combined with spectral interval selection using genetic algorithm for prediction of constituents in pharmaceutical solid dosage forms from near infrared chemical imaging data. Journal of Near Infrared Spectroscopy, v. 24, p. 157-169, 2016.

 Ribeiro, L.N.M.; Franz-Montan, M.;  Breitkreitz, M.C.; Alcântara, A.C.S.; Castro, S.R.; Guilherme, V.A.; Barbosa, R.M.; de Paula, E. Nanostructured lipid carriers as robust systems for topical lidocaine-prilocaine release in dentistry. European Journal of Pharmaceutical Sciences, v. 93, p. 192-202, 2016.

 Breitkreitz, M.C.; Souza, A. M.; Poppi, R.J. A didactic chemometrics experiment for design of experiments (DOE): evaluation of experimental conditions in the spectrophotometric determination of Iron II with o -phenanthroline. A tutorial, part III. Química Nova, v. 37, p. 564-573, 2014.

 Breitkreitz, M.C.; Sabin, G. P. ; Polla, G; Ronei J.P. Characterization of semi- solid Self-Emulsifying Drug Delivery Systems (SEDDS) of atorvastatin calcium by Raman image spectroscopy and chemometrics. Journal of Pharmaceutical and Biomedical Analysis, v. 73, p. 3-12, 2013.

 de Campos, R.P; Yoshida, I.V.P.; Breitkreitz, M.C.;  Poppi, R.J. ; da Silva, J.A.F. Raman imaging spectroscopic characterization of modified poly(dimethylsiloxane) for micro total analysis systems applications. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy , , v. 100,p. 67-71, 2013.

 Breitkreitz, M.C.; Souza, A.M.; Rohwedder, J.J.R.; Poppi, R.J. Experimento didático de quimiometria para calibração multivariada na determinação de paracetamol em comprimidos comerciais utilizando espectroscopia no infravermelho próximo: um tutorial, parte II. Química Nova, v. 36, p. 1057-1065, 2013.

 Sabin, G.P.; Souza, A.M.;  Breitkreitz, M.C.; Poppi, R.J. Desenvolvimento de um algoritmo para identificação e correção de spikes em espectroscopia raman de imagem. Química Nova, v. 35, p. 612-615, 2012.

 Castro e Silva, C.C.; Breitkreitz, M.C.; Santhiago, M.; Corrêa, C. C.;  Kubota, L.T.   Construction of a new functional platform by grafting poly(4-vinylpyridine) in multi-walled carbon nanotubes for complexing copper ions aiming the amperometric detection of l-cysteine. Electrochimica Acta, v. 71, p. 150-158, 2012.

 Breitkreitz, M.C.; Poppi, R. Trends in Raman Chemical Imaging. Biomedical Spectroscopy and Imaging, v. 2, p. 159, 2012.

 Sabin, G.P.; Breitkreitz, M.C.; Souza, A.M.; Fonseca, P.; Calefe, L.; Moffa, M.; Poppi, R.J. Analysis of pharmaceutical pellets: An approach using near- infrared chemical imaging. Analytica Chimica Acta, v. 706, p. 113-119, 2011.

 Breitkreitz, M.C.;  Jardim, I.C.S.F. ;  Bruns, R.E. Combined column mobile phase mixture statistical design optimization of high-performance liquid chromatographic analysis of multicomponent systems. Journal of Chromatography, v. 1216, p. 1439-1449, 2009.

 Ferreira, S. L.;  Bruns, R.E. ; Silva, E G.P. ; Santos, W.N.L.;  Quintella, C. M. ; David, J.M.; Andrade, J.B.; Breitkreitz, M.C.;  ; Jardim, I.C.S.F.; Barros Neto, B. Statistical designs and response surface techniques for the optimization of chromatographic systems. Journal of Chromatography, v. 1158, p. 2-14, 2007.

 Borges, C.; Breitkreitz, M.C.;  Bruns, R.E. ; Silva, L.M.; Scarminio, I.S. Unreplicated split-plot mixture designs and statistical models for optimizing mobile chromatographic phase and extraction solutions for fingerprint searches. Chemometrics and Intelligent Laboratory Systems, v. 89, p. 82-89, 2007.

 Breitkreitz, M.C.; Pasquini, C.; Raimundo Jr., I.V.; Rohwedder, J.J.R.;  Dantas Filho, H.A. ; Araujo, M.C.U.; Jose, G.E. Determination of total sulphur in diesel employing NIR spectroscopy and multivariate calibration. Analyst, v. 128, p.1204-1207, 2003

Trabalhos premiados em congressos

 “Avaliação da restrição de correlação para alcançar a vantagem de segunda ordem em dados de primeira ordem: Um estudo em dados simulados”. Igor Miranda Santana, Licarion Pinto, Márcia Cristina Breitkreitz. X Workshop de Quimiometria 2019, 22-25/04/2019, UFBA, Salvador, BA.

 “Otimização de método por UHPSFC para análise de vitaminas lipossolúveis e hidrossolúveis empregando conceitos de Analytical Quality by Design”. Fernando H. P. Bruhn, Lucília Vilela de Melo, Isabel Cristina S. F. Jardim, Márcia C. Breitkreitz. IX Workshop de Quimiometria, 23-27/04/2018, Natal, RN, Brasil.

 “Desenvolvimento de método indicativo de estabilidade para a associação losartana potássica e besilato de anlodipino empregando os conceitos de Analytical Quality by Design”. Leandro P. Sacchi, Licarion Pinto, Márcia Cristina Breitkreitz. III Simpósio em Ciências Farmacêuticas, 2018, Belo Horizonte.

 “Analytical challenges associated with the separation and quantification of bioactive compounds from palm oil by ultra-high performance supercritical fluid chromatography”. Cesar C. Santana, Luciana S. Guedes, José L. P. Segundo Neto, Douglas N. Rutledge, Marisa M. Beppu, Lucília V. Melo, Isabel C. S. F. Jardim, Márcia C. Breitkreitz. 45th Internacional Symposium on High Performance Liquid Phase Separations and Related Techniques, 18- 22/06/2017, Prague, Czech Republic.

 “Factorial design of nanostructured lipid carriers (NLC) based on beeswax and copaiba oil for lidocaine encapsulation”. Lígia N. M. Ribeiro, Eneida de Paula, Márcia C. Breitkreitz. III Winter School on Chemometrics, 24-26/07/2017, Araraquara, São Paulo, Brazil.

 “Optimization and characterization of lipid nanoparticles for lidocaine- prilocaine sustained release using experimental design”, Ribeiro, L.N.M.; Franz-Montan M.; Barbosa, R.M.; Alcântara, A.C.S.; Guilherme, V.A.; Castro, S.R.;Breitkreitz, M.C.; de Paula, E., 10th International Congress on Pharmaceutical Sciences, 05-09/09/2015, Ribeirão Preto, São Paulo, Brasil.